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Also reported in: mcg/L, µg/L
Your serum tryptase is in the normal range. This is reassuring for systemic mastocytosis and mast cell activation disorder surveillance.
Your serum tryptase is undetectable. Tryptase is stored in mast cell granules and released during mast cell activation. An undetectable level is the ideal result, indicating no significant mast cell degranulation.
No action needed.
Serum tryptase undetectable — no significant mast cell activationYour serum tryptase is within the normal reference range. A normal baseline tryptase makes systemic mastocytosis unlikely and indicates no chronic mast cell activation.
No action needed.
Serum tryptase within normal reference range — no evidence of mast cell activation disorderYour serum tryptase is in the low-normal range with no clinically significant mast cell activation.
No action needed.
Serum tryptase: low-normal — no clinically significant mast cell activationYour serum tryptase is in the normal range. This is reassuring for systemic mastocytosis and mast cell activation disorder surveillance.
No specific action required.
Serum tryptase within reference range — normal mast cell baselineYour serum tryptase is in the optimal range, reflecting minimal mast cell degranulation and excellent baseline mast cell health.
No action needed.
Serum tryptase: optimal — minimal mast cell granule releaseYour serum tryptase is above the reference range. An elevated baseline tryptase raises concern for systemic mastocytosis or mast cell activation syndrome. Tryptase above 11.4 ng/mL is one of the WHO minor criteria for systemic mastocytosis.
Seek allergy/immunology referral. Bone marrow biopsy, KITD816V mutation testing, urine prostaglandins, and comprehensive mast cell evaluation are indicated. Symptoms of MCAS (flushing, hives, anaphylaxis, GI symptoms) should be documented.
Serum tryptase 11.4–20 ng/mL — borderline elevated; systemic mastocytosis or MCAS possibleYour serum tryptase is significantly elevated. At this level, systemic mastocytosis is highly suspected. This condition involves pathological mast cell accumulation in the bone marrow, skin, liver, spleen, and GI tract, and can cause organ dysfunction and anaphylaxis.
Seek urgent hematology/allergy specialist referral. Bone marrow biopsy is typically required for diagnosis. KIT mutation testing and comprehensive organ assessment are needed.
Serum tryptase >20 ng/mL — elevated; systemic mastocytosis highly suspected; organ involvement possibleYour serum tryptase is critically elevated. A tryptase above 75 ng/mL in the acute setting confirms anaphylaxis. In a non-acute setting, this level is consistent with aggressive systemic mastocytosis with significant mast cell burden and potential for multi-organ damage. This level requires emergency evaluation.
Seek emergency medical care immediately if symptomatic. Epinephrine is the first-line treatment for anaphylaxis. If non-acute, seek urgent hematology evaluation — aggressive systemic mastocytosis may require cytoreductive therapy.
Serum tryptase >75 ng/mL — critically elevated; anaphylaxis confirmed or aggressive mastocytosisUpload your lab report and get your actual values interpreted in plain English — instantly, with no medical training required.