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Also reported in: mcg/L
Your tacrolimus level is within the target therapeutic range, providing effective immunosuppression to prevent organ rejection while minimizing toxicity risk.
Your tacrolimus level is far below the therapeutic range, providing virtually no immunosuppression. There is a very high risk of acute organ rejection. This is an emergency for transplant recipients.
Contact your transplant team immediately. A significant dose increase is needed urgently. Do not miss any doses.
Tacrolimus: {{value}} {{unit}} — critically low (therapeutic: {{low}}–{{high}})Your tacrolimus level is below the target range for your transplant type and time post-transplant. The risk of acute rejection is increased. The specific target depends on the organ (kidney: 5–15, liver: 5–20, heart: 10–20) and time since transplant.
Discuss with your transplant team. A dose adjustment is typically needed. Trough levels should be measured consistently before the morning dose.
Tacrolimus: {{value}} {{unit}} — subtherapeutic (target: {{low}}–{{high}})Your tacrolimus level is at the lower end of or slightly below the target. For stable patients further out from transplant, lower targets are sometimes acceptable.
Discuss with your transplant team. If you are stable with good graft function and no evidence of rejection, this level may be acceptable.
Tacrolimus: {{value}} {{unit}} — borderline lowYour tacrolimus level is within the target therapeutic range, providing effective immunosuppression to prevent organ rejection while minimizing toxicity risk.
Continue current dosing. Continue routine monitoring of tacrolimus levels, kidney function, blood glucose, and blood pressure.
Tacrolimus: {{value}} {{unit}} — within therapeutic range ({{low}}–{{high}})Your tacrolimus level sits in the optimal therapeutic window for your condition — providing excellent immunosuppression with manageable side effects.
Continue current regimen. Regular monitoring is essential.
Tacrolimus: {{value}} {{unit}} — at optimal levelYour tacrolimus level is above the target range. Early side effects include mild tremor, headache, hypertension, and a slight increase in serum creatinine. The risk of nephrotoxicity increases with higher levels.
Discuss with your transplant team. A dose reduction may be considered. Monitor kidney function closely.
Tacrolimus: {{value}} {{unit}} — borderline highYour tacrolimus level is above the therapeutic range. Tacrolimus is nephrotoxic at high levels, causing acute kidney injury. Other toxicities include noticeable tremor, seizures, posterior reversible encephalopathy syndrome (PRES), high potassium, and hypertension.
Contact your transplant team urgently. Hold or reduce the dose. Monitor kidney function, electrolytes, and blood pressure closely. noticeable neurotoxicity requires immediate medical attention.
Tacrolimus: {{value}} {{unit}} — supratherapeutic (target: {{low}}–{{high}})A critically high tacrolimus level can cause noticeable nephrotoxicity requiring dialysis, neurotoxicity including PRES (posterior reversible encephalopathy syndrome) with seizures and visual loss, life-threatening infections (over-immunosuppression), and thrombotic microangiopathy.
This is a medical emergency. Hold tacrolimus immediately and contact your transplant team. Close monitoring in the hospital is usually required. Treatment may need to be changed to alternative immunosuppressants.
Tacrolimus: {{value}} {{unit}} — critically high (target: {{low}}–{{high}})Upload your lab report and get your actual values interpreted in plain English — instantly, with no medical training required.