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Also reported in: mcg/L
Your NSE is in the normal range. Note that hemolyzed blood samples give falsely elevated NSE, so sample quality must be confirmed if results are unexpected.
Your NSE is undetectable. NSE is an enzyme found in neurons and neuroendocrine cells. An undetectable level is the best possible baseline result for small cell lung cancer and neuroendocrine tumor surveillance.
No action needed.
NSE undetectable — no detectable neuron-specific enolaseYour NSE is within the normal reference range. This is a reassuring result. NSE is primarily used to monitor small cell lung cancer and neuroendocrine tumor treatment response.
No action needed. If you smoke, comprehensive lung cancer screening (low-dose CT) per guidelines is recommended.
NSE within normal reference range — no elevated neuroendocrine/small cell lung markerYour NSE is in the low-normal range. This is a favorable baseline finding.
No action needed.
NSE: low-normal — favorable baselineYour NSE is in the normal range. Note that hemolyzed blood samples give falsely elevated NSE, so sample quality must be confirmed if results are unexpected.
No specific action required.
NSE within reference range — normal neuroendocrine marker levelYour NSE is in the optimal range, which is a very reassuring baseline for neuroendocrine and lung cancer health.
No action needed.
NSE: optimal — very low marker levelYour NSE is above the reference range. Mildly elevated NSE commonly results from hemolysis of the blood sample (red cell lysis releases NSE), benign brain injury, and seizures. Small cell lung cancer and other neuroendocrine tumors must also be considered.
Ensure the sample was non-hemolyzed before acting on this result. Discuss with your doctor. Chest CT and clinical assessment for lung symptoms are warranted if sample quality is confirmed.
NSE 16.3–25 ng/mL — borderline elevated; hemolysis and benign causes must be excludedYour NSE is significantly elevated (assuming non-hemolyzed sample). At this level, small cell lung carcinoma, large cell neuroendocrine carcinoma, or other neuroendocrine tumors are a serious concern. NSE correlates with disease activity in SCLC.
Seek specialist oncology or pulmonology referral. CT chest and dedicated neuroendocrine tumor workup should be arranged promptly.
NSE >25 ng/mL — significantly elevated; neuroendocrine or small cell lung tumor evaluation requiredYour NSE is critically elevated, strongly associated with active, often advanced, small cell lung cancer or neuroendocrine malignancy with significant tumor burden. Very high NSE in known SCLC indicates extensive disease.
Seek urgent specialist oncology evaluation immediately. Comprehensive staging CT/PET and treatment planning must begin without delay.
NSE >100 ng/mL — critically elevated; active small cell or neuroendocrine malignancy highly likelyUpload your lab report and get your actual values interpreted in plain English — instantly, with no medical training required.