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Also reported in: mcmol/L
Your methotrexate level is below the toxicity threshold (<0.1 µmol/L at 42 hours or <0.05 µmol/L at 72 hours). This indicates the drug has been adequately cleared and leucovorin rescue is working.
Your methotrexate level is very low, which is the goal 42+ hours after high-dose methotrexate infusion. This indicates that methotrexate has been effectively cleared from your body.
Reassuring result. Continue leucovorin rescue as directed.
Methotrexate: {{value}} {{unit}} — very low (expected)Your methotrexate level is low and below the toxicity threshold, indicating adequate clearance of the drug. Leucovorin rescue can continue as scheduled.
Continue leucovorin rescue as directed. No dose adjustment needed.
Methotrexate: {{value}} {{unit}} — low (expected)Your methotrexate level is below the toxicity threshold (<0.1 µmol/L at 42 hours or <0.05 µmol/L at 72 hours). This indicates the drug has been adequately cleared and leucovorin rescue is working.
Continue leucovorin rescue per protocol. Monitoring will continue until MTX level is <0.05 µmol/L.
Methotrexate: {{value}} {{unit}} — within safe range (<{{high}} {{unit}})Your methotrexate level is very low, indicating excellent clearance. The risk of MTX toxicity is very low.
Continue leucovorin rescue per protocol.
Methotrexate: {{value}} {{unit}} — safe and well-clearedYour methotrexate level is above the ideal clearance threshold but not yet in the danger zone. This suggests slightly delayed elimination. Dehydration, kidney impairment, or drug interactions can slow MTX clearance.
Contact your doctor. IV fluids should be increased and leucovorin dose may need to be increased or continued longer. Monitor creatinine and MTX levels closely.
Methotrexate: {{value}} {{unit}} — borderline high — increased monitoring neededYour methotrexate level is above the target threshold, indicating delayed clearance. High MTX levels can cause noticeable toxicities including myelosuppression, mucositis, acute kidney injury, hepatitis, and neurotoxicity.
Contact your doctor urgently. Increase IV fluids, increase leucovorin dose and frequency, and consider alkalinizing urine. Monitor kidney function and MTX levels every 12–24 hours until cleared.
Methotrexate: {{value}} {{unit}} — elevated (target: <{{high}} {{unit}})A critically high methotrexate level represents delayed clearance with a high risk of noticeable, potentially life-threatening toxicity including pancytopenia, noticeable mucositis, acute kidney failure requiring dialysis, actual liver damage from the drug, and cerebral edema.
This is a medical emergency. Contact the treating oncology team immediately. Aggressive leucovorin rescue (high-dose, every 6 hours), IV fluids, urinary alkalinization, and consideration of glucarpidase (carboxypeptidase G2) are needed. ICU admission likely.
Methotrexate: {{value}} {{unit}} — critically high (target: <{{high}} {{unit}})Upload your lab report and get your actual values interpreted in plain English — instantly, with no medical training required.