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Also reported in: pmol/L
Your peak nocturnal melatonin is within the normal reference range. This is a reassuring result for sleep and circadian health.
Your peak nocturnal melatonin is critically low. Melatonin is the master hormone of sleep and circadian rhythm regulation. A critically low peak indicates noticeable melatonin deficiency, which prevents normal sleep onset, destroys sleep architecture, and disrupts circadian-regulated body processes including immune function, DNA repair, and metabolic timing.
Seek medical evaluation. Complete darkness in the sleeping environment, elimination of blue light exposure after sunset, and melatonin supplementation (0.5–5 mg physiological dose, 30 minutes before bed) should be considered. Endocrine and neurological assessment may be warranted.
Nocturnal melatonin critically low (<5 pg/mL) — noticeable melatonin deficiency; circadian rhythm failedYour peak nocturnal melatonin is below the reference range. Low melatonin production leads to delayed sleep onset, reduced slow-wave and REM sleep, non-restorative sleep, and circadian rhythm disruption. Common causes include age-related pineal decline, light pollution at night, blue light exposure from screens, and certain medications (beta-blockers, NSAIDs, benzodiazepines).
Discuss with your doctor. Practice sleep hygiene: complete darkness at night, eliminating blue light 2 hours before sleep, consistent sleep/wake times. Physiological-dose melatonin supplementation (0.5–1 mg) may be beneficial. Review medications that suppress melatonin.
Nocturnal melatonin below reference range (<20 pg/mL) — melatonin deficiency; sleep disruption likelyYour nocturnal melatonin is at the lower end of normal. Suboptimal melatonin may contribute to delayed sleep onset or reduced sleep quality.
Improve sleep hygiene — reduce blue light exposure in the evening, maintain darkness during sleep, keep consistent sleep timing.
Nocturnal melatonin: low-normal — suboptimal sleep hormone productionYour peak nocturnal melatonin is within the normal reference range. This is a reassuring result for sleep and circadian health.
No specific action required.
Nocturnal melatonin within reference range — adequate sleep hormone productionYour nocturnal melatonin is in the optimal range, indicating excellent pineal gland function and a well-regulated circadian rhythm. Optimal melatonin is associated with better sleep quality, stronger immunity, better antioxidant protection, and potential longevity benefits.
No action needed. Continue practices supporting healthy melatonin production.
Nocturnal melatonin in optimal range (>80 pg/mL) — excellent sleep hormone productionYour nocturnal melatonin is above the reference range. This most commonly reflects exogenous melatonin supplementation (many OTC supplements contain 5–10 mg, which produces supraphysiological levels). Natural high melatonin in young people is not unusual.
If supplementing, consider reducing to a physiological dose (0.5–1 mg) which is often more effective than high doses. Discuss with your doctor.
Nocturnal melatonin above reference range — very high melatonin; possible supplement useYour nocturnal melatonin is significantly elevated. This level likely reflects melatonin supplementation. Very high melatonin from supplementation can cause morning grogginess and theoretical reproductive suppression with long-term use.
Reduce melatonin supplementation dose to 0.5–3 mg. Discuss optimal dosing with your doctor.
Nocturnal melatonin significantly elevated — high supplementation or rare pineal hypersecretionYour nocturnal melatonin is very elevated. This is almost always due to very high-dose supplementation. Rarely, a pineal gland tumor (pinealoma) can cause melatonin excess. Morning grogginess and circadian disruption can occur with very high levels.
Review and significantly reduce melatonin supplementation. Discuss with your doctor. If not taking supplements, pituitary/pineal MRI should be considered.
Nocturnal melatonin critically elevated — very high supplementation; pineal tumor rare considerationUpload your lab report and get your actual values interpreted in plain English — instantly, with no medical training required.