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Also reported in: nmol/L
A normal IGF-1 suggests your pituitary–liver axis is producing enough growth-hormone signal to match typical 24-hour activity for your age bracket. IGF-1 peaks in adolescence, settles through your 20s, and gently declines thereafter; a reading in the normal range is what most healthy adults show. On its own this value is neither a flag nor a diagnosis — it's a quiet check in the routine-physiology column.
IGF-1 (insulin-like growth factor 1) is made mostly by the liver in response to growth hormone pulses, and because it hangs around in the blood for hours, it gives a steadier picture of 24-hour GH activity than a single GH measurement. A low value can reflect an underactive pituitary, chronic undernutrition (especially low protein intake), poor or fragmented sleep, significant weight loss, or reduced muscle mass. IGF-1 also drifts down naturally with age, so interpret against an age- and sex-matched range rather than a single adult cutoff. Low IGF-1 is not itself a disease, but in combination with fatigue, decreased strength, or unexplained weight loss it can warrant workup for pituitary issues.
If this is paired with fatigue, shrinking muscle, or slow post-exercise recovery, bring it up with your doctor. The low-effort lifestyle moves that consistently nudge IGF-1 up are deep sleep (7+ hours), adequate daily protein (~1.2–1.6 g/kg for active adults), and a meaningful weekly dose of heavy resistance training. Re-testing in 3–6 months captures the change.
IGF-1: {{value}} {{unit}} — low (ref: {{low}}–{{high}})A normal IGF-1 suggests your pituitary–liver axis is producing enough growth-hormone signal to match typical 24-hour activity for your age bracket. IGF-1 peaks in adolescence, settles through your 20s, and gently declines thereafter; a reading in the normal range is what most healthy adults show. On its own this value is neither a flag nor a diagnosis — it's a quiet check in the routine-physiology column.
Nothing to act on. The lifestyle levers that support GH pulses (deep sleep, protein, resistance training) are worth keeping regardless of whether this specific number is high or low.
IGF-1: {{value}} {{unit}} — normal (ref: {{low}}–{{high}})Observational cohort studies have repeatedly found that both very low and very high IGF-1 are associated with less favorable outcomes — low IGF-1 with frailty and cardiovascular events, high IGF-1 with certain cancers. Mid-range values are consistently tied to the best long-term outcomes. Landing here suggests a well-balanced GH axis that is active enough to maintain tissue, but not so loud that it pushes proliferative signaling.
This is a favorable read. Maintain the foundations (sleep, protein, training) and recheck in a year unless something symptomatic changes.
IGF-1: {{value}} {{unit}} — optimal rangeElevated IGF-1 most commonly reflects exogenous growth hormone or IGF-1 use (including some peptide supplements that are marketed as GH secretagogues). In rarer cases, a markedly elevated level points toward a GH-secreting pituitary adenoma and, if persistent, can cause acromegaly. Epidemiologically, sustained high IGF-1 has been associated with a modestly increased risk of colorectal, breast, and prostate cancers across several large cohort studies, though the individual-level risk contribution is small. A single elevated reading is not diagnostic of anything; confirmation with a repeat draw, IGFBP-3, and possibly a GH suppression test is how clinicians differentiate cause.
Confirm with a repeat measurement in 4–6 weeks before acting. If you're taking GH, a GH secretagogue, or an IGF-1-raising peptide, your prescribing provider should see this number. Persistent elevation with symptoms (enlarging hands/feet/jaw, headaches, sweating) warrants endocrinology referral.
IGF-1: {{value}} {{unit}} — elevated (ref: {{low}}–{{high}})Upload your lab report and get your actual values interpreted in plain English — instantly, with no medical training required.