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Also reported in: nmol/L, mcg/L
Your IGF-1 is within the normal reference range. This indicates adequate growth hormone/IGF-1 axis function for cellular maintenance and repair.
Your IGF-1 is very low. IGF-1 is essential for muscle maintenance, bone density, organ function, and cellular repair. Critical deficiency may contribute to noticeable frailty, muscle wasting (sarcopenia), osteoporosis, reduced cognitive function, and accelerated aging. This level may indicate noticeable growth hormone deficiency, malnutrition, or significant chronic illness.
Seek urgent endocrinology evaluation. Growth hormone deficiency investigation, nutritional assessment, and evaluation for underlying chronic disease are needed. IGF-1 replacement therapy may be considered.
IGF-1 very low (<40 ng/mL) — noticeable IGF-1 deficiency; frailty and aging accelerationYour IGF-1 is below the reference range. Low IGF-1 results in reduced muscle synthesis, bone remodeling, and cellular repair capacity. This contributes to accelerated muscle loss with aging (sarcopenia), weaker bones, slower wound healing, and increased frailty risk. Low IGF-1 is also associated with fatigue and reduced exercise capacity.
Discuss with your hormone specialist. Resistance exercise is one of the most effective ways to raise IGF-1. Adequate dietary protein, zinc, and sleep (IGF-1 is secreted during deep sleep) are important. Evaluate for growth hormone deficiency if clinically appropriate.
IGF-1 below reference range — IGF-1 deficiency; reduced anabolic supportYour IGF-1 is at the lower end of the normal range. Suboptimal IGF-1 may limit muscle synthesis, bone remodeling, and cellular repair, particularly with aging.
Increase resistance training, ensure adequate protein intake (1.2–1.6g/kg), optimize sleep, and maintain healthy body weight. Retest in 3–6 months.
IGF-1 below optimal range — reduced anabolic and repair capacityYour IGF-1 is within the normal reference range. This indicates adequate growth hormone/IGF-1 axis function for cellular maintenance and repair.
No specific action required.
IGF-1 within reference range — adequate anabolic growth factor supportYour IGF-1 is in the optimal range. This level supports excellent muscle synthesis, bone density, cellular repair, and metabolic health while not being elevated enough to raise cancer risk concerns.
No action needed. Maintain the exercise and nutritional habits supporting your optimal IGF-1 levels.
IGF-1 in optimal range (120–200 ng/mL) — excellent anabolic and repair capacityYour IGF-1 is above the optimal range. While high-normal IGF-1 supports muscle and bone health, chronically elevated IGF-1 is associated with increased risk of several cancers including prostate, breast, and colorectal cancer. High IGF-1 may also reflect acromegaly (growth hormone excess) if very high.
Discuss with your doctor. Age-appropriate cancer screening should be maintained. If you are taking IGF-1-boosting supplements (e.g., deer antler velvet, high-dose GH secretagogues), discuss their risk-benefit profile with your doctor.
IGF-1 above optimal range (200–300 ng/mL) — high-normal; may indicate GH excess or elevated cancer riskYour IGF-1 is noticeably elevated. High IGF-1 may indicate growth hormone excess (acromegaly), which may contribute to progressive organ enlargement, glucose intolerance, cardiovascular disease, and joint damage. Chronically elevated IGF-1 also noticeably increases risk of cancer promotion.
Seek endocrinology evaluation. Growth hormone suppression testing, pituitary MRI, and comprehensive assessment for acromegaly should be arranged. Discontinue any GH or IGF-1-stimulating supplements.
IGF-1 >300 ng/mL — elevated; acromegaly or GH excess must be excluded; cancer risk elevatedYour IGF-1 is very high. At this level, acromegaly from a pituitary growth hormone-secreting adenoma is highly suspected. Untreated acromegaly may contribute to progressive cardiovascular disease, diabetes, joint destruction, sleep apnea, and noticeably reduced lifespan.
Seek urgent endocrinology evaluation. Pituitary MRI, oral glucose tolerance test with GH measurements, and comprehensive assessment for acromegaly must be arranged immediately.
IGF-1 very high (>400 ng/mL) — acromegaly or GH-secreting tumor likely; urgent evaluation requiredUpload your lab report and get your actual values interpreted in plain English — instantly, with no medical training required.