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Also reported in: ng/mL, µg/L
Your plasma histamine is in the normal range, consistent with no active allergic reaction or histamine dysregulation at the time of testing.
Your plasma histamine is undetectable. Histamine is a signaling molecule released during allergic reactions and by mast cells. An undetectable level indicates no active histamine excess.
No action needed.
Plasma histamine undetectable — no excess histamine in circulationYour plasma histamine is within the normal reference range. This is a reassuring result for mast cell activation and histamine intolerance assessment.
No action needed.
Plasma histamine within normal reference range — no excess histamine activityYour plasma histamine is in the low-normal range with no clinically significant excess.
No action needed.
Plasma histamine: low-normal — no clinically significant histamine elevationYour plasma histamine is in the normal range, consistent with no active allergic reaction or histamine dysregulation at the time of testing.
No specific action required.
Plasma histamine within reference range — normal histamine activityYour histamine is in the optimal range, reflecting very low circulating histamine and minimal mast cell activation.
No action needed.
Plasma histamine: optimal — minimal histamine burdenYour plasma histamine is above the normal reference range. Elevated histamine can result from acute allergic reaction (timed sampling important), mast cell activation disorder (MCAD), histamine intolerance (low DAO enzyme activity), or high-histamine diet (aged cheeses, wine, fermented foods, fish). Symptoms include headache, flushing, hives, GI disturbance, and itching.
Discuss with your doctor. DAO enzyme activity testing, histamine-rich food diary review, and mast cell assessment should be considered. A low-histamine elimination diet trial may be informative.
Plasma histamine above reference range — elevated histamine; mast cell activation or histamine intoleranceYour plasma histamine is significantly elevated. This level suggests significant mast cell activation, noticeable histamine intolerance, or an active allergic reaction at time of sampling. Mast cell activation syndrome (MCAS) and systemic mastocytosis should be considered.
Seek allergy/immunology specialist evaluation. Serum tryptase, 24-hour urine histamine metabolites, and bone marrow evaluation may be appropriate. A low-histamine diet and antihistamine therapy may provide symptom relief while evaluation proceeds.
Plasma histamine significantly elevated — significant histamine excess; mast cell disorder or noticeable histamine intoleranceYour plasma histamine is critically elevated at levels consistent with an active or very recent anaphylactic reaction. This level is associated with systemic mast cell degranulation, causing life-threatening cardiovascular collapse, bronchospasm, and angioedema.
Seek emergency medical care immediately if symptomatic. Epinephrine administration may be required. Comprehensive mast cell disorder evaluation should follow acute stabilization.
Plasma histamine critically elevated — anaphylactic levels; emergency evaluation requiredUpload your lab report and get your actual values interpreted in plain English — instantly, with no medical training required.