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Also reported in: g/L
Your gamma globulin fraction is normal, reflecting adequate immunoglobulin production and a healthy immune system.
A critically low gamma fraction indicates noticeable hypogammaglobulinemia — a significant deficiency of antibodies. This can be congenital (common variable immunodeficiency, X-linked agammaglobulinemia) or acquired (chronic lymphocytic leukemia, multiple myeloma, immunosuppressive therapy).
Seek urgent medical evaluation. Quantitative immunoglobulins (IgG, IgA, IgM) and immunology consultation are needed. Intravenous immunoglobulin (IVIG) therapy may be indicated.
Gamma globulin: {{value}} {{unit}} — critically low (ref: {{low}}–{{high}})Low gamma globulin can indicate reduced antibody production (hypogammaglobulinemia). Causes include primary immunodeficiencies, medications (corticosteroids, immunosuppressants), protein-losing conditions, or hematologic malignancies.
See your doctor. Quantitative immunoglobulin levels (IgG, IgA, IgM) should be measured to determine the nature and severity of the deficiency.
Gamma globulin: {{value}} {{unit}} — below reference range (ref: {{low}}–{{high}})A borderline low gamma fraction may represent mild antibody deficiency or a normal variant. It is worth monitoring, especially if you experience frequent infections.
Discuss with your doctor if you have recurrent infections, autoimmune conditions, or a family history of immunodeficiency.
Gamma globulin: {{value}} {{unit}} — borderline lowYour gamma globulin fraction is normal, reflecting adequate immunoglobulin production and a healthy immune system.
No action needed.
Gamma globulin: {{value}} {{unit}} — within reference rangeYour gamma globulin sits in the healthy midrange, reflecting robust and balanced antibody production.
No action needed.
Gamma globulin: {{value}} {{unit}} — optimalA borderline high gamma fraction often reflects polyclonal activation of the immune system from chronic infection, autoimmune disease, or chronic inflammation. Small M-spikes may also produce this pattern.
If persistent, discuss with your doctor. Immunofixation can differentiate polyclonal from monoclonal (M-spike) increases.
Gamma globulin: {{value}} {{unit}} — borderline highElevated gamma globulin can be polyclonal (from chronic infections, autoimmune diseases like SLE or rheumatoid arthritis, or chronic liver disease) or monoclonal (from a plasma cell disorder like monoclonal gammopathy of undetermined significance or multiple myeloma).
See your doctor. Immunofixation to detect an M-spike, quantitative immunoglobulins, and clinical evaluation are needed to determine the cause.
Gamma globulin: {{value}} {{unit}} — above reference range (ref: {{low}}–{{high}})A critically elevated gamma fraction most commonly indicates a monoclonal gammopathy — a large paraprotein spike from a plasma cell proliferative disorder such as multiple myeloma, Waldenström's macroglobulinemia, or MGUS (monoclonal gammopathy of undetermined significance).
Seek urgent medical evaluation. Immediate hematology consultation with immunofixation, serum free light chain assay, and bone marrow evaluation may be needed.
Gamma globulin: {{value}} {{unit}} — critically high (ref: {{low}}–{{high}})Upload your lab report and get your actual values interpreted in plain English — instantly, with no medical training required.