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Also reported in: nmol/L
The adrenal glands produced a normal surge of cortisol in response to synthetic ACTH. This rules out both Addison's disease and Cushing's disease with high confidence.
The adrenal glands failed to mount a normal cortisol surge after ACTH stimulation. This is the gold-standard finding for hypoadrenocorticism (Addison's disease). Early or atypical Addison's may have normal electrolytes initially.
Your vet will likely start your dog on hormone replacement therapy (e.g., desoxycorticosterone pivalate and prednisone). Electrolytes should also be checked for high potassium and hyponatremia.
Canine post-ACTH cortisol: 4 µg/dL (Low)The adrenal glands produced a normal surge of cortisol in response to synthetic ACTH. This rules out both Addison's disease and Cushing's disease with high confidence.
No action needed. Your dog's adrenal function is normal.
Canine post-ACTH cortisol: 14 µg/dLAn exaggerated cortisol response to ACTH is the hallmark of pituitary-dependent hyperadrenocorticism (Cushing's disease). Adrenal tumor Cushing's usually has a similar exaggerated response but is less common.
Your vet may perform a low-dose dexamethasone suppression test or an abdominal ultrasound to differentiate pituitary from adrenal Cushing's. Treatment options include trilostane or mitotane.
Canine post-ACTH cortisol: 25 µg/dL (High)Upload your lab report and get your actual values interpreted in plain English — instantly, with no medical training required.