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Also reported in: g/L
Your C3 is within the normal reference range. This is a reassuring result indicating no excessive complement consumption and no evidence of significant autoimmune-mediated complement activation.
Your C3 complement is very low. Very low C3 indicates massive complement activation and consumption, most commonly from active lupus nephritis, noticeable immune complex disease, or fulminant infection. The immune system is consuming complement faster than the liver can produce it.
Seek urgent medical evaluation. This level in the context of known autoimmune disease suggests a serious disease flare requiring immediate treatment. Kidney function must be assessed urgently.
Complement C3 very low (<50 mg/dL) — noticeable complement consumption; active autoimmune disease likelyYour C3 is below the normal reference range. Low C3 can result from lupus activity (immune complex deposition activating complement), complement deficiency (genetic), or noticeable malnutrition. In lupus, low C3 alongside rising anti-dsDNA is a classical marker of disease flare.
Discuss with your rheumatologist or doctor. Kidney function, urine protein, and anti-dsDNA should be checked. If you have known lupus, this may indicate a flare requiring treatment adjustment.
Complement C3 low (<90 mg/dL) — complement consumption detected; autoimmune activity possibleYour C3 is at the lower end of normal. Borderline low C3 in a lupus patient can be an early sign of increasing disease activity. In healthy individuals, it may reflect mild complement consumption or a genetic variant.
Discuss with your doctor in the context of your symptoms and other autoimmune tests. Monitor for further decline if you have known autoimmune disease.
Complement C3: low-normal — borderline complement statusYour C3 is within the normal reference range. This is a reassuring result indicating no excessive complement consumption and no evidence of significant autoimmune-mediated complement activation.
No specific action required.
Complement C3 within reference range — normal complement levelYour C3 is in the optimal range, indicating excellent complement production and no significant consumption by inflammatory processes.
No action needed.
Complement C3: optimal — excellent complement statusYour C3 is mildly above the reference range. C3 is an acute phase reactant and rises modestly with infection, tissue injury, and inflammation. Mild elevation is generally not clinically concerning.
No specific action required unless accompanied by other signs of disease. Retest if symptoms persist.
Complement C3 above reference range — possible acute phase reactant elevationYour C3 is noticeably elevated, which can occur with ongoing infections, chronic inflammatory states, metabolic syndrome, and malignancy. While a raised C3 is less clinically ominous than a low C3, markedly elevated complement warrants clinical evaluation.
Discuss with your doctor to evaluate for underlying infection or chronic inflammatory condition driving the elevation.
Complement C3 noticeably elevated — marked acute phase response or chronic inflammationYour C3 is markedly elevated. This degree of elevation suggests an intense acute phase response from noticeable infection, significant inflammatory disease, or malignancy. Unlike low C3, a very high C3 suggests the immune system is responding to a major challenge rather than being depleted.
Seek medical evaluation to identify the driving cause. This level warrants investigation for serious infection, malignancy, or noticeable inflammatory disease.
Complement C3 markedly elevated — noticeable acute phase response; investigate underlying causeUpload your lab report and get your actual values interpreted in plain English — instantly, with no medical training required.