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Also reported in: index
Your anti-tTG IgA is in the normal range. This is the expected negative result for celiac disease screening in an individual consuming gluten.
No anti-tTG IgA antibodies were detected. Anti-tTG IgA is the primary serological marker for celiac disease with high sensitivity (~93%) and specificity (~98%). A negative result makes celiac disease very unlikely.
No action needed. A negative anti-tTG IgA makes celiac disease unlikely but does not completely exclude seronegative celiac disease or IgA deficiency (which gives false negatives).
Anti-tTG IgA: negative — no anti-tissue transglutaminase antibodies detectedYour anti-tTG IgA is within the normal reference range. This is a reassuring result for celiac disease screening.
No action needed.
Anti-tTG IgA within normal reference range — no celiac disease antibodyYour anti-tTG IgA is at a low-normal level with no clinically significant celiac disease antibody.
No action needed.
Anti-tTG IgA: low-normal — no significant celiac antibodyYour anti-tTG IgA is in the normal range. This is the expected negative result for celiac disease screening in an individual consuming gluten.
No specific action required.
Anti-tTG IgA within reference range — normal celiac disease screening resultYour anti-tTG IgA is in the optimal range with no detectable celiac disease antibody. This is the best possible baseline result.
No action needed.
Anti-tTG IgA: optimal — undetectable celiac disease antibodyYour anti-tTG IgA is in the borderline-positive range. This equivocal result requires further evaluation. Low-positive anti-tTG IgA can occur with other autoimmune conditions and does not definitively confirm celiac disease. However, celiac disease cannot be excluded and warrants further testing.
Seek gastroenterology evaluation. Anti-EMA IgA, total serum IgA, and HLA-DQ2/DQ8 testing should be arranged. Small bowel biopsy via endoscopy may be recommended while still consuming gluten.
Anti-tTG IgA 4–10 U/mL — borderline positive; equivocal; further celiac evaluation requiredYour anti-tTG IgA is clearly positive. This result is highly suggestive of celiac disease. In children with anti-tTG IgA values greater than 10x the upper limit of normal, ESPGHAN guidelines allow diagnosis without biopsy. Adults require small bowel biopsy to confirm villous atrophy before adopting a lifelong gluten-free diet.
Seek urgent gastroenterology evaluation. Do not start a gluten-free diet before completing the diagnostic work-up (endoscopy + biopsies). Once confirmed, a strict lifelong gluten-free diet is the only treatment.
Anti-tTG IgA >10 U/mL — positive; celiac disease highly likely; small bowel evaluation requiredYour anti-tTG IgA is critically elevated, which is strongly associated with active celiac disease and significant small intestinal villous atrophy (Marsh III). At this level, malabsorption of iron, B12, folate, calcium, fat-soluble vitamins, and other nutrients is likely occurring and causing systemic effects.
Seek urgent gastroenterology evaluation. Endoscopy should be arranged as a priority while on a gluten-containing diet. Nutritional deficiency assessment (iron, B12, folate, vitamin D, calcium) should be done simultaneously.
Anti-tTG IgA >50 U/mL — highly positive; celiac disease confirmed or strongly suspected; significant gut damage likelyUpload your lab report and get your actual values interpreted in plain English — instantly, with no medical training required.