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Also reported in: IU/mL
Your ANCA-PR3 is in the normal range. This is a reassuring result for vasculitis surveillance.
No anti-PR3 antibodies were detected. Anti-PR3 is the specific marker for granulomatosis with polyangiitis (GPA, formerly Wegener's granulomatosis). A negative result makes GPA unlikely.
No action needed.
ANCA-PR3: negative — no anti-PR3 antibodies detectedYour ANCA-PR3 is within the normal reference range. This is a reassuring result for GPA surveillance.
No action needed.
ANCA-PR3: negative — within reference range; no GPA-specific antibodyYour ANCA-PR3 is at a low-negative level with no clinically significant vasculitis-related antibody.
No action needed.
ANCA-PR3: low-negative — no clinically significant antibodyYour ANCA-PR3 is in the normal range. This is a reassuring result for vasculitis surveillance.
No specific action required.
ANCA-PR3: negative — normal baselineYour ANCA-PR3 is in the optimal range with no detectable vasculitis-specific antibody.
No action needed.
ANCA-PR3: optimal — undetectable vasculitis markerYour ANCA-PR3 is above the reference range. Mildly elevated ANCA-PR3 may be a false positive or an early finding in granulomatosis with polyangiitis. GPA affects the upper respiratory tract, lungs, and kidneys, and can be rapidly progressive if untreated.
Seek specialist rheumatology or nephrology evaluation. Urinalysis for red cell casts, chest X-ray, kidney function tests, and ENT assessment are important. Repeat testing to confirm this.
ANCA-PR3 above reference range — borderline positive; GPA evaluation requiredYour ANCA-PR3 is noticeably elevated. High ANCA-PR3 is highly specific for granulomatosis with polyangiitis (GPA). GPA may contribute to destructive inflammation of blood vessels in the upper airways, lungs, and kidneys, and can cause rapid kidney failure and respiratory failure if not treated promptly.
Seek urgent rheumatology or nephrology referral. Kidney biopsy, chest CT, nasal/sinus assessment, and urinalysis with microscopy are all important. GPA requires prompt immunosuppressive treatment.
ANCA-PR3 noticeably elevated — granulomatosis with polyangiitis highly suspectedYour ANCA-PR3 is very high, consistent with active or relapsing granulomatosis with polyangiitis with significant organ damage risk. Rapidly progressive glomerulonephritis (kidney failure) and pulmonary hemorrhage are life-threatening complications of noticeable GPA.
Seek emergency medical evaluation immediately. GPA at this level may cause irreversible kidney failure or fatal pulmonary hemorrhage without immediate immunosuppressive treatment.
ANCA-PR3 very high — active GPA vasculitis with organ damage risk; emergency evaluation requiredUpload your lab report and get your actual values interpreted in plain English — instantly, with no medical training required.