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Also reported in: mcg/dL
Your SHBG (a protein that grabs onto sex hormones) (a protein that carries sex hormones in your blood) is within the normal range, indicating appropriate balance between bound and free sex hormones.
Very low SHBG (a protein that grabs onto sex hormones) (a protein that carries sex hormones in your blood) is a strong marker of noticeable insulin resistance, type 2 diabetes, obesity, or metabolic syndrome. While more testosterone is technically 'free,' the underlying metabolic state is very unhealthy and is associated with high cardiovascular risk.
Seek medical evaluation for insulin resistance and metabolic syndrome. This level of SHBG (a protein that grabs onto sex hormones) (a protein that carries sex hormones in your blood) is an independent cardiovascular and diabetes risk marker.
SHBG (a protein that carries sex hormones in your blood): {{value}} {{unit}} — very low (ref: {{low}}–{{high}})Low SHBG (a protein that grabs onto sex hormones) (a protein that carries sex hormones in your blood) is a reliable marker of insulin resistance, obesity, type 2 diabetes, and metabolic syndrome. It is also lowered by high testosterone, anabolic steroids, growth hormone, and thyroid conditions. While low SHBG (a protein that grabs onto sex hormones) means more free testosterone, the context of why it is low matters enormously.
Address metabolic health factors — reduce excess weight, improve insulin sensitivity through diet and exercise, reduce sugar and refined carbohydrates. Check fasting insulin and HbA1c (a 3-month average of your blood sugar).
SHBG (a protein that carries sex hormones in your blood): {{value}} {{unit}} — below reference range (ref: {{low}}–{{high}})Borderline low SHBG (a protein that grabs onto sex hormones) (a protein that carries sex hormones in your blood) is an early indicator of insulin resistance or metabolic stress. It can also occur with high dietary protein, obesity, or hypothyroidism.
Evaluate fasting glucose, insulin, and HbA1c (a 3-month average of your blood sugar). Address any metabolic risk factors through diet and exercise.
SHBG (a protein that carries sex hormones in your blood): {{value}} {{unit}} — borderline lowYour SHBG (a protein that grabs onto sex hormones) (a protein that carries sex hormones in your blood) is within the normal range, indicating appropriate balance between bound and free sex hormones.
No action needed. Good result.
SHBG (a protein that carries sex hormones in your blood): {{value}} {{unit}} — within reference rangeYour SHBG (a protein that grabs onto sex hormones) (a protein that carries sex hormones in your blood) is in the healthy midrange, indicating a well-regulated balance between binding and releasing sex hormones for cellular use.
Excellent result. No action needed.
SHBG (a protein that carries sex hormones in your blood): {{value}} {{unit}} — optimalBorderline high SHBG (a protein that grabs onto sex hormones) (a protein that carries sex hormones in your blood) means somewhat more testosterone is bound and unavailable to cells. This can be associated with hyperthyroidism, high estrogen, aging, high fiber diet, or certain medications.
Check free testosterone to confirm this whether biologically active testosterone is adequate. If symptoms of low testosterone exist, discuss with your doctor.
SHBG (a protein that carries sex hormones in your blood): {{value}} {{unit}} — borderline highHigh SHBG (a protein that grabs onto sex hormones) (a protein that carries sex hormones in your blood) binds most of the available testosterone in the blood, leaving very little free testosterone to reach cells. You may feel symptoms of low testosterone (fatigue, low libido, muscle loss) even if total testosterone appears normal. Causes include hyperthyroidism, liver disease, aging, and certain medications.
Check free testosterone to assess actual bioavailable hormone. Address underlying may contribute to — hyperthyroidism treatment, weight training, and reducing alcohol can help normalize SHBG (a protein that grabs onto sex hormones) (a protein that carries sex hormones in your blood).
SHBG (a protein that carries sex hormones in your blood): {{value}} {{unit}} — above reference range (ref: {{low}}–{{high}})Very high SHBG (a protein that grabs onto sex hormones) (a protein that carries sex hormones in your blood) essentially inactivates all available testosterone — causing profound functional hypogonadism even with technically normal total testosterone. This is seen in noticeable hyperthyroidism, advanced liver disease, and anorexia nervosa.
Seek urgent medical evaluation. The cause of very large SHBG (a protein that grabs onto sex hormones) (a protein that carries sex hormones in your blood) elevation must be identified and treated. Free testosterone will be very low in this context.
SHBG (a protein that carries sex hormones in your blood): {{value}} {{unit}} — very high (ref: {{low}}–{{high}})Upload your lab report and get your actual values interpreted in plain English — instantly, with no medical training required.