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Also reported in: µmol/L, nmol/mL
Your NAD+ is within the reference range. This indicates adequate cellular energy metabolism and sirtuin pathway support.
Your NAD+ is very low. NAD+ is the central molecule in cellular energy metabolism, DNA repair, sirtuin longevity pathway activation, and mitochondrial function. Critical NAD+ depletion very impairs cellular energy production, halts DNA repair processes, deactivates sirtuins (longevity proteins), and accelerates biological aging across all organ systems.
Seek medical evaluation. NAD+ restoring levels therapy (NMN, NR supplementation, or IV NAD+ infusion) should be discussed with a longevity medicine specialist. Underlying may contribute to (alcohol use, niacin deficiency, chronic illness) should be assessed.
NAD+ very low (<5 mcM) — noticeable cellular energy deficiency; sirtuin activity impairedYour NAD+ is below the reference range. Declining NAD+ with age is a fundamental driver of the aging process, contributing to mitochondrial dysfunction, impaired DNA repair, reduced sirtuin activity, and cellular senescence. Low NAD+ manifests as fatigue, cognitive decline, metabolic dysfunction, and accelerated biological aging.
Discuss NAD+ precursor supplementation with your doctor (NMN or NR). Evidence-based lifestyle strategies to boost NAD+ include exercise, caloric restriction/intermittent fasting, adequate protein intake with tryptophan and niacin, and reducing alcohol consumption.
NAD+ below reference range (<10 mcM) — cellular energy deficit; aging accelerationYour NAD+ is below the optimal range. Suboptimal NAD+ impairs sirtuin activity, reduces mitochondrial efficiency, and may contribute to fatigue and slower cellular repair.
Consider NAD+ precursor supplementation (NMN or NR) under medical guidance. Regular exercise, reduced alcohol intake, and adequate dietary niacin support NAD+ levels.
NAD+ borderline low (10–20 mcM) — suboptimal cellular energy metabolismYour NAD+ is within the reference range. This indicates adequate cellular energy metabolism and sirtuin pathway support.
No specific action required. Maintaining NAD+ through exercise and healthy diet is beneficial.
NAD+ within reference range — adequate cellular energy metabolismYour NAD+ is in the optimal range. This level supports excellent cellular energy production, active DNA repair, robust sirtuin (longevity protein) activity, and mitochondrial health.
No action needed. Continue lifestyle practices that maintain optimal NAD+ levels.
NAD+ in optimal range (20–50 mcM) — excellent cellular energy and longevity supportYour NAD+ is above the typical optimal range. This may reflect effective NAD+ precursor supplementation or a constitutionally high NAD+ production capacity. High NAD+ is generally favorable for cellular energy and longevity pathways.
No specific concern. If supplementing, discuss appropriate dosing with your doctor.
NAD+ above optimal range — well-supplemented or constitutionally high NAD+ metabolismYour NAD+ is noticeably elevated. This level typically reflects active NAD+ precursor supplementation (NMN, NR, or IV NAD+). Elevated NAD+ is generally considered beneficial, though very high levels from aggressive supplementation have not been broadly studied long-term.
Discuss current supplement dosing with your doctor. Very high NAD+ from supplementation may not provide additional benefit over optimal levels.
NAD+ noticeably elevated — likely reflects active NAD+ supplementationYour NAD+ is very elevated. This level likely reflects aggressive NAD+ supplementation. While NAD+ itself is generally safe, very high levels should be monitored to ensure no adverse effects from the supplementation protocol.
Discuss with your doctor or longevity specialist. Consider reducing NAD+ precursor supplementation to achieve optimal rather than maximal levels.
NAD+ markedly elevated — very high; likely aggressive supplementation; monitorUpload your lab report and get your actual values interpreted in plain English — instantly, with no medical training required.