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Also reported in: ng/mL, mcg/total overnight urine
Your urinary 6-sulphatoxymelatonin is within the normal reference range, indicating adequate overnight melatonin production.
Your 6-sulphatoxymelatonin (the main melatonin metabolite in urine) is critically low, confirming very impaired melatonin production throughout the night. This reflects near-total disruption of the pineal melatonin rhythm with serious consequences for sleep, immune function, and circadian biology.
Seek medical evaluation. Implement strict sleep hygiene, complete darkness during sleep, blue light elimination in the evening, and discuss melatonin supplementation with your doctor.
Urinary 6-sulphatoxymelatonin critically low — very impaired melatonin production overnightYour overnight melatonin metabolite is below the reference range, confirming reduced melatonin secretion during sleep. This is the most reliable way to assess total overnight melatonin output. Low urinary melatonin is associated with disturbed sleep, circadian misalignment, increased oxidative stress, and reduced nighttime immune activation.
Implement sleep hygiene: complete bedroom darkness, blue light reduction 2+ hours before bed, consistent sleep timing. Discuss melatonin supplementation with your doctor. Review medications that suppress melatonin (beta-blockers, NSAIDs).
Urinary 6-sulphatoxymelatonin below reference range — reduced overnight melatonin productionYour urinary melatonin metabolite is at the lower end of normal. Suboptimal overnight melatonin production may contribute to sleep quality issues.
Improve evening light exposure management and sleep timing consistency.
Urinary 6-sulphatoxymelatonin: low-normal — suboptimal overnight melatonin outputYour urinary 6-sulphatoxymelatonin is within the normal reference range, indicating adequate overnight melatonin production.
No specific action required.
Urinary 6-sulphatoxymelatonin within reference range — adequate overnight melatonin productionYour overnight melatonin production is in the optimal range, reflecting excellent pineal gland function and circadian rhythm health.
No action needed.
Urinary 6-sulphatoxymelatonin in optimal range — excellent overnight melatonin productionYour urinary melatonin metabolite is above the reference range. This may reflect melatonin supplementation or constitutionally high melatonin production.
If supplementing, discuss optimal dosing with your doctor. Naturally high melatonin is generally not a concern.
Urinary 6-sulphatoxymelatonin above reference range — high melatonin production or supplementationYour overnight melatonin metabolite is significantly elevated. This likely reflects melatonin supplementation. Very high melatonin may cause morning grogginess.
Reduce melatonin supplementation dose and discuss with your doctor.
Urinary 6-sulphatoxymelatonin significantly elevated — high supplementation levelsYour overnight melatonin metabolite is critically elevated, reflecting very high melatonin supplementation.
Discuss with your doctor and significantly reduce melatonin supplementation dose.
Urinary 6-sulphatoxymelatonin critically elevated — very high supplementation; review doseUpload your lab report and get your actual values interpreted in plain English — instantly, with no medical training required.