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Your cortisol (the stress hormone) and DHEA-S (a partner-hormone to cortisol) (the regeneration hormone) are in reasonable balance. This suggests your adrenal glands are managing stress without depleting your reserves.
A very low cortisol-to-DHEA ratio may indicate very low cortisol production (adreduced kidney function) or unusually high DHEA. Either situation represents a serious adrenal hormonal imbalance.
Seek urgent endocrinology evaluation to assess adrenal function.
Cortisol:DHEA-S Ratio: {{value}} — very low (ref: {{low}}–{{high}})A low ratio can suggest that cortisol production is reduced relative to DHEA. This pattern can be seen in early adrenal fatigue recovery or in people with naturally high DHEA.
Discuss your adrenal function profile with your doctor.
Cortisol:DHEA-S Ratio: {{value}} — below reference range (ref: {{low}}–{{high}})A borderline low ratio may represent slight adrenal imbalance. Context matters here — it could be completely normal for some individuals.
No immediate action, but monitor alongside other adrenal markers.
Cortisol:DHEA-S Ratio: {{value}} — borderline lowYour cortisol (the stress hormone) and DHEA-S (a partner-hormone to cortisol) (the regeneration hormone) are in reasonable balance. This suggests your adrenal glands are managing stress without depleting your reserves.
No action needed. Good adrenal balance.
Cortisol:DHEA-S Ratio: {{value}} — within reference rangeYour cortisol-to-DHEA ratio is in the ideal range, indicating that your body is managing stress well while maintaining regenerative hormone reserves.
Excellent result. This reflects good adrenal resilience.
Cortisol:DHEA-S Ratio: {{value}} — optimalA mildly elevated ratio suggests your stress hormone cortisol is getting higher relative to DHEA-S (a partner-hormone to cortisol). Chronic stress gradually depletes DHEA while keeping cortisol elevated, leading to burnout over time.
Focus on stress management, sleep quality, and recovery time. This is an early warning signal.
Cortisol:DHEA-S Ratio: {{value}} — borderline elevatedA high cortisol-to-DHEA ratio is a strong sign of chronic stress overload. Cortisol is dominating while your regenerative DHEA reserves have been depleted. This is what is colloquially called 'adrenal fatigue' and is associated with exhaustion, immune suppression, and hormonal cascades.
Address chronic stressors urgently. Discuss DHEA support, adaptogenic herbs, and cortisol management with your functional medicine or endocrinology doctor.
Cortisol:DHEA-S Ratio: {{value}} — elevated (ref: {{low}}–{{high}})A very high cortisol-to-DHEA ratio indicates noticeable adrenal dysfunction, possibly Cushing's syndrome (too much cortisol production) or complete DHEA depletion. This level has serious consequences for immune function, metabolism, and mental health.
Urgent endocrinology evaluation is needed to investigate adrenal function and rule out Cushing's syndrome.
Cortisol:DHEA-S Ratio: {{value}} — very high (ref: {{low}}–{{high}})Upload your lab report and get your actual values interpreted in plain English — instantly, with no medical training required.