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Also reported in: IU/mL
Your ANCA-MPO is in the normal range. This is a reassuring result for MPO-ANCA-associated vasculitis surveillance.
No anti-MPO antibodies were detected. Anti-MPO is the primary marker for microscopic polyangiitis (MPA) and eosinophilic granulomatosis with polyangiitis (EGPA/Churg-Strauss). A negative result makes these conditions less likely.
No action needed.
ANCA-MPO: negative — no anti-myeloperoxidase antibodies detectedYour ANCA-MPO is within the normal reference range. This is a reassuring result for MPO-ANCA vasculitis surveillance.
No action needed.
ANCA-MPO: negative — within reference range; no MPO-ANCA vasculitis markerYour ANCA-MPO is at a low-negative level with no clinically significant vasculitis-related antibody.
No action needed.
ANCA-MPO: low-negative — no clinically significant antibodyYour ANCA-MPO is in the normal range. This is a reassuring result for MPO-ANCA-associated vasculitis surveillance.
No specific action required.
ANCA-MPO: negative — normal baselineYour ANCA-MPO is in the optimal range with no detectable MPO-ANCA vasculitis antibody.
No action needed.
ANCA-MPO: optimal — undetectable MPO vasculitis markerYour ANCA-MPO is above the reference range. Mild elevation can indicate early microscopic polyangiitis, drug-induced ANCA vasculitis (hydralazine, propylthiouracil, minocycline), or a false positive. MPA primarily affects the kidneys and lungs.
Discuss with your doctor. Urinalysis for red cell casts, kidney function tests, chest imaging, and medication review should be arranged. Repeat testing to confirm this elevation.
ANCA-MPO above reference range — borderline positive; MPA or drug-induced ANCA evaluation neededYour ANCA-MPO is noticeably elevated. High ANCA-MPO is strongly associated with microscopic polyangiitis (MPA) and eosinophilic granulomatosis with polyangiitis. MPA may contribute to rapidly progressive glomerulonephritis and pulmonary capillaritis, which can lead to kidney failure and respiratory failure without prompt treatment.
Seek urgent rheumatology or nephrology referral. Kidney biopsy and comprehensive organ assessment are needed. MPA requires prompt immunosuppressive treatment to prevent irreversible organ damage.
ANCA-MPO noticeably elevated — microscopic polyangiitis or EGPA highly suspectedYour ANCA-MPO is very high, consistent with active MPO-ANCA vasculitis. Rapidly progressive glomerulonephritis and pulmonary hemorrhage are serious, potentially fatal complications of noticeable MPO-ANCA vasculitis and require emergency medical management.
Seek emergency medical evaluation immediately. Intensive immunosuppressive treatment with high-dose steroids and rituximab or cyclophosphamide may be life-saving. Do not delay.
ANCA-MPO very high — active MPO-ANCA vasculitis with organ-threatening inflammationUpload your lab report and get your actual values interpreted in plain English — instantly, with no medical training required.